Advertisement
Review Article|Articles in Press

What Frequency of Ankle Pump Exercise is Optimal to Improve Lower Limb Hemodynamics? A Systematic Review and Network Meta-Analysis

  • Author Footnotes
    † Xin Wang and Rongsong Tang have contributed equally to this work and share first authorship.
    Xin Wang
    Footnotes
    † Xin Wang and Rongsong Tang have contributed equally to this work and share first authorship.
    Affiliations
    Institute of Sports Medicine, Peking University Third Hospital, Huayuan North Road No.49, Haidian District, Beijing, China
    Search for articles by this author
  • Author Footnotes
    † Xin Wang and Rongsong Tang have contributed equally to this work and share first authorship.
    Rongsong Tang
    Footnotes
    † Xin Wang and Rongsong Tang have contributed equally to this work and share first authorship.
    Affiliations
    Nursing Department, Peking University Third Hospital, Huayuan North Road No.49, Haidian District, Beijing, China
    Search for articles by this author
  • Heli Zhang
    Affiliations
    Department of Rehabilitation Medicine, Peking University Third Hospital, Huayuan North Road No.49, Haidian District, Beijing, China
    Search for articles by this author
  • Fan Li
    Affiliations
    Department of Neurosurgery, Peking University Third Hospital, Huayuan North Road No.49, Haidian District, Beijing, China
    Search for articles by this author
  • Jing Wang
    Affiliations
    Nursing Department, Peking University Third Hospital, Huayuan North Road No.49, Haidian District, Beijing, China
    Search for articles by this author
  • Baohua Li
    Correspondence
    Corresponding author. , Tel.: +86 13911380138.
    Affiliations
    Nursing Department, Peking University Third Hospital, Huayuan North Road No.49, Haidian District, Beijing, China
    Search for articles by this author
  • Author Footnotes
    † Xin Wang and Rongsong Tang have contributed equally to this work and share first authorship.
Open AccessPublished:March 16, 2023DOI:https://doi.org/10.1016/j.anr.2023.03.001
      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Purpose

      Ankle pump exercises (APE) have been widely used in clinical practice. However, best practices for APE have not been established. Recognize the most effective frequency of APE for improving lower extremity hemodynamics and establish recommendations in clinical practice.

      Methods

      A systematic review and network meta-analysis (NMA) was performed according to PRISMA-NMA. Six English databases (Pubmed, Medline, CINAHL, Embase, the Cochrane library and ProQuest) and four Chinese databases (CNKI, Wanfang, VIP and Sinomed) were searched. Randomized controlled trials (RCTs) and quasi-experimental studies investigating the effects of different frequencies of APE on lower limb hemodynamics published before July 2022 were included. The reference list was also searched. Seven studies (one RCTs and six quasi-experimental studies) were included in the systematic review and five studies (one RCTs and four quasi-experimental studies) were included in the NMA. risk of bias was assessed using the Cochrane and Joanna Briggs Institute tools. the NMA was performed using the R software (version 4.2.1) and OpenBUGS (version 3.2.3).

      Results

      The results of the NMA showed that a frequency of every 3-4 seconds was the most effective in improving lower extremity hemodynamics (P=0.85), followed by every 1-2 seconds (P=0.81), every 5-6 seconds (P=0.32) and less than every 10 seconds (P=0.02). Subgroup analysis failed to find a difference between healthy participants and those with unilateral total hip arthroplasty or fracture (MD=-0.23, 95% CI -5.92 to 4.61).

      Conclusions

      For adult patients, with or without lower extremity disease, a frequency of every 3-4 seconds can be recommended as the optimal frequency of APE in clinical care practice.

      Text Words