Asian Nursing Research
Volume 2, Issue 3 , Pages 159-165, September 2008

Assessment of Salivary Human Herpesvirus-6 and Immunoglobulin A Levels in Nurses Working Shifts

  • Hirom Fukuda, RN, PhD

      Affiliations

    • Associate Professor, Oita University of Nursing and Health Sciences, Oita, Japan
    • Corresponding Author InformationCorrespondence to: Hiromi Fukuda, RN, PhD, Oita University of Nursing and Health Sciences, 2944-9 Megusuno, Oita 870-1201, Japan
    • ,
  • Takamichi Ichinose, PhD

      Affiliations

    • Dean and Professor, Oita University of Nursing and Health Sciences, Oita, Japan
    • ,
  • Tomoko Kusama, RN, PHN, PhD

      Affiliations

    • President and Professor, Oita University of Nursing and Health Sciences, Oita, Japan
    • ,
  • Reico Sakurai, RN, PHN, MS

      Affiliations

    • President and Professor, Oita University of Nursing and Health Sciences, Oita, Japan

Received 9 June 2008; received in revised form 9 June 2008; accepted 8 September 2008.

Article Outline

Purpose

The purpose of the present study was to assess whether salivary human herpesvirus (HHV)-6 acted as a new sensitive stress marker, providing a reliable indicator of stress among shift work nurses. Salivary HHV-6, immunoglobulin (Ig) A and mood states were compared among nurses who worked day shifts only and nurses who worked different numbers of night shifts.

Methods

Participants included 56 female nurses working in Japanese general hospitals. The 56 subjects were categorized into three groups: Group A (n = 7), which consisted of nurses who only worked day shifts; group B (n = 29), which consisted of nurses working shifts with £8 night shifts per month; and group C (n = 20), which consisted of nurses working shifts with 3 9 night shifts per month. Mood was assessed using the Profile of Mood States Short Form Japanese version (POMS-SFJ). Salivary biomarker levels and mood were compared among the three groups.

Results

Although the salivary HHV-6 level was significantly higher in group C than in group A (p < .05), salivary IgA and mood levels were not significantly different among the three groups.

Conclusion

Salivary HHV-6 level may be a more sensitive stress marker than salivary IgA or mood for assessing chronic fatigue in nurses working shifts. Improvement to shift assignments using assessment by salivary HHV-6 is required.

Key Words:  chronic fatigue assessment , nurses , salivary human herpesvirus-6 , shift work

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PII: S1976-1317(08)60039-0

doi:10.1016/S1976-1317(08)60039-0

Asian Nursing Research
Volume 2, Issue 3 , Pages 159-165, September 2008

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